The Brain Performance Index

The Brain Performance Index (BPI) is an estimate of the efficiency of neural resource allocation and it is not designed to replace a neuropsychological test but rather to compliment neuropsychological evaluations especially where a patient has problems taking a conventional neuropsychological test or when one wants to rapidly repeat the test. The Weschler Intelligence test  (i.e., mazes, coding, block design, digit span, picture completion, math, vocabulary, verbal I.Q., performance I.Q., full scale I.Q) and the EEG was recorded from 19 channels with a linked ears reference in the eyes closed condition from 339 normal control subjects, age 6 to 18 years of age.  EEG variables that correlated at P < .01 were entered into a multivariate regression  analysis called the Brain Performance Index (BPI) in which individual neuropsychological sub-tests were the dependent variable and EEG Phase delays, EEG coherence, EEG amplitude asymmetry and EEG power were the independent variables.  The multivariate regression  equations, referred to as the Predicted Neuropsychological Score  (PNS) also computes the + and – 95% confidence band as a EEG prediction of performance on each neuropsychological test.  The correlation to I.Q. was approximately 0.58 and involved short time delays between the frontal lobes and the rest of the brain (faster resource allocation, elevated power (more energy) and lower coherence (high complexity).   These three combined measures give rise to an overall prediction of the efficiency of neural resource allocation.

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 FIG1.  DSCOREs w_ DQFULL, DQVERB, DQPERF.jpg (44063 bytes)     FIG2.  HISTOs_DISCRIMINANT FUNCTIONs.jpg (53526 bytes)     FIG4.  VALIDATING the Predictive Multiple Regression Equations.jpg (48824 bytes)     Fig. 6 - Rendered Brains.jpg (43022 bytes)


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